Helminth-Induced Immune Regulation: Implications for Immune Responses to Tuberculosis
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منابع مشابه
Helminth-Induced Immune Regulation: Implications for Immune Responses to Tuberculosis
Tuberculosis (TB) caused by the bacteriaMycobacterium tuberculosis (Mtb) remains a global cause of considerable morbidity and mortality [1]. One of the biggest current challenges of TB control is our incomplete understanding of what constitutes protective immunity in TBendemic areas of the world. Although close to 2,200 million people maintain the infection in a state of latency and act as a re...
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Despite marked improvement in the quality of lives across the globe, more than 2 million individuals in socioeconomically disadvantaged environments remain infected by helminth (worm) parasites. Owing to the longevity of the worms and paucity of immunologic controls, these parasites survive for long periods within the bloodstream, lymphatics, and gastrointestinal tract resulting in pathologic c...
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Use of highly active antiretroviral treatment (HAART) has had a major impact on HIV-associated morbidity and mortality in industrialized countries. Access to HAART is now expanding in low-income countries where tuberculosis (TB) is the most important opportunistic disease. The incidence of TB has been fueled by the HIV epidemic and in many countries with high HIV prevalence current TB control m...
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ژورنال
عنوان ژورنال: PLOS Pathogens
سال: 2015
ISSN: 1553-7374
DOI: 10.1371/journal.ppat.1004582